A device for holding an endotracheal tube has a slide track configured to fit adjacent a lip on a patients face. The track has a face contacting side, an exposed side, and a pair of opposite ends. A tube holder is coupled to and slidable along the track. A positioning mechanism is releasably lockable to allow selective lateral repositioning of the tube holder and an endotracheal tube held thereby along the track and to retain the tube holder at a selected position along the track without removing the device from the patient or an endotracheal tube from the device. A bite block is carried by the tube holder and slidable therewith along the track. The bite block has a tubular wall with a central opening along a length of the bite block and a pair of opposite open ends. The bite block is positioned spaced vertically from the track and has a portion extending rearward beyond the face contacting side of the track.