Disclosed is a chemical composition comprising one or more bridged polycyclic based compounds of the formula (Ia) or (I), wherein the substituents are as described within the specification. Further disclosed is the use of said chemical composition in the manufacture of a medicament for treating a fungal infection, an infection, a viral infection, a bacteria-based disease, a microbial-based disease, mold-based disease, yeast-based disease, and/or results from parasitic invasion of a subject.