Jianhua Yu,Steven Devine,Michael A. Caligiuri,Shun He
申请号：
US15860612
公开号：
US20180207202A1
申请日:
2018.01.02
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed are methods of mobilizing hematopoietic cells in a subject by administering to the subject a combination of Flt3 ligand (FLT3L) and a cell adhesion inhibitor. Also disclosed are methods of mobilizing hematopoietic cells in a cell culture population by contacting the cell culture population with Flt3 ligand. Mobilized hematopoietic cells can subsequently be harvested and used for hematopoietic cell transplantation. Further disclosed are compositions comprising a FLT3L, compositions comprising FLT3L and a cell adhesion inhibitor, and composition comprising FLT3L and Plerixafor.
