The present invention relates to novel amidomethyl-substituted oxindolederivativesof formula (I)(see formula I)pharmaceutical agents containing same, and the use thereof for the treatmentofvasopressin-dependent illnesses. In formula (I), R1 is hydrogen, methoxy orethoxy; R2 is hydrogen ormethoxy; R3 is hydrogen, methyl, ethyl, n-propyl or isopropyl; and X1 and X2are N or CH,with the proviso that X1 and X2 are not both N at the same time.