Maqsood Ahmed Chotani,John Anthony Bauer,Mandar Shankar Joshi,Selvi Chrysolyte Jeyaraj
申请号：
US13458079
公开号：
US20120301402A1
申请日:
2012.04.27
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A method for assessing if a subject has or is at risk of developing cardiac arrhythmia is described. The method includes determining the activity of Rap1A protein in a bodily sample of the subject and comparing the activity of Rap1A protein from the bodily sample of the subject to at least one Rap1A control. A decreased level of Rap1A activity in the bodily sample of the subject as compared to the at least one Rap1A control indicates that the subject is at risk of developing or has cardiac arrhythmia. Methods for evaluating the efficacy of treatment of a subject having decreased Rap1A activity with an antiarrhythmic agent are also described.
