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ANTIRETROVIRAL COMBINATION
专利权人:
СИПЛА ЛИМИТЕД (IN)
发明人:
ЛУЛЛА Амар (IN),МАЛХОТРА Джина (IN)
申请号:
RU2014111723/15
公开号:
RU2014111723A
申请日:
2014.03.26
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A pharmaceutical composition for use in the treatment of HIV or AIDS, comprising a solid dosage form comprising: (i) a first granule (granules) comprising ritonavir or a pharmaceutically acceptable salt thereof, an ester or solvate, and a water-insoluble polymer and / or soluble a polymer in water; (ii) a second granule (s) comprising darunavir or a pharmaceutically acceptable salt, ester or solvate thereof. 2. The pharmaceutical composition of claim 1, wherein the dosage form is a capsule or sachet containing said first granule (granules) and a second granule (granules). The pharmaceutical composition of claim 1, wherein the ritonavir solvate is ritonavir hydrate. The pharmaceutical composition of claim 1, wherein the darunavir solvate is darunavir hydrate. A pharmaceutical composition for use in the treatment of HIV or AIDS, comprising a solid dosage form comprising: (i) a first tablet (s) comprising ritonavir or a pharmaceutically acceptable salt thereof, an ester or solvate, and a water-insoluble polymer and / or water-soluble polymer; (ii) a second tablet (s) comprising darunavir or a pharmaceutically acceptable salt, ester or solvate thereof. 6. The pharmaceutical composition of claim 5, wherein the first tablet (s) and the second tablet (s) are placed in a capsule or sachet. The pharmaceutical composition of claim 5, wherein the ritonavir solvate is ritonavir hydrate. The pharmaceutical composition of claim 5, wherein the darunavir solvate is darunavir hydrate. A pharmaceutical composition for use in the treatment of HIV or AIDS, comprising a solid dosage form, including1. Фармацевтическая композиция для применения в лечении HIV или AIDS, включающая твердую лекарственную форму, включающую:(i) первую гранулу (гранулы), включающую ритонавир или его фармацевтически приемлемую соль, сложный эфир или сольват, и нерастворимый в воде полимер и/или растворимый в воде полимер;(ii) вторую гранулу (гранулы), включающую дарунавир или его фармацевтически приемлемую сол
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