The object of the present invention is to provide a bone substitute material, medical material containing the bone substitute material and process for producing the bone substitute material wherein the bone material has excellent mechanical strength, biological affinity and biological activity. The present invention provides a bone substitute material comprising a titanium or a titanium alloy and an anodic oxide film of the titanium or titanium alloy, wherein the anodic oxide film is formed on a surface of the titanium or titanium alloy, wherein inorganic compound microparticles are firmly fixed to a surface and/or inside of the anodic oxide film, and wherein the inorganic compound contains at least phosphorus and calcium. The present invention further provides a medical material comprising the bone substitute material and a method for manufacturing the bone substitute material.
