AYERS, MARK D.,LUNCEFORD, JARED K.,MCCLANAHAN, TERRILL K.,MURPHY, ERIN E.,NEBOZHYN, MICHAEL,LOBODA, ANDREY
申请号：
CA2968406
公开号：
CA2968406A1
申请日:
2015.12.08
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
A gene expression platform, which is a combination of a set of genes that are correlated with response to a PD-1 antagonist in multiple tumor types and a normalization gene set, is disclosed. A method and system of using the gene expression platform to derive gene signature biomarkers of anti-tumor response to a PD-1 antagonist and to test patient samples for predictive gene signature biomarkers are also disclosed.
