The present invention relates to a method for the preparation of particles comprising the steps a) providing a solution A, which comprises water and Maltodextrin of the types DE 13.0 - 17.0 or DE 16.5 - 19.5, b) providing a solution B, which comprises acetone as and at least one poloxamer and c) combining solution A with solution B. Furthermore, the invention is directed to a particle comprising Maltodextrin and no protein, obtainable by said method, as well as to a particle comprising Maltodextrin and a protein, obtainable by said method if solution A further comprises at least one protein.