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A PROCESS FOR OBTAINING MICROCAPSULES
专利权人:
SIPCAM S.P.A.
发明人:
BERNARDINI, MARCO,BORGO, FRANCESCA,FRESCHI, GIORGIO,RUSSO, EDOARDO
申请号:
RSP20180115
公开号:
RS56800B1
申请日:
2012.05.04
申请国别(地区):
RS
年份:
2018
代理人:
摘要:
A continuous process for preparing microcapsules containing water-insoluble active principle, for use in the pharmaceutical and agrochemical field, comprising: (1) preparation in a first reactor under stirring of an aqueous solution containing one or more surfactants, (2) preparation in a second reactor under stirring of a solution comprising at least an active principle immiscible in an aqueous phase and the first component for preparing the polycondensation polymer forming the microcapsule shell, simultaneous feeding to a tubular reactor of a stream of the aqueous solution (1) and of a stream of solution (2), being the ratio stream solution (2)/stream solution (1) comprised between 0.5 and 2.0, streams (1), and (2) being under turbulent flow conditions in the tubular reactor, streams (1) and (2 being continuously fed to the tubular reactor.
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