A method for providing a preparation of tumor specific T lymphocytes, which comprises the steps of: A.Select clones of tumor specific T lymphocytes: - providing a tumor Sample obtained from a patient - preparation of Isolating Nucleic Acid in a sample of the tumor.Isolation of nucleic acid Pa obtaining a Plurality of nucleic acid sequences of the Receptor of T lymphocytes from the preparation of nucleic acid or a Plurality of STRI ng + Garter SetAmino Acid sequences of t-cell receptor encoded by the Plurality of nucleic acid sequences of the Receptor of T lymphocytes - selecting a Nucleic Acid Sequence of PrayPtor of tumor specific T lymphocytes of the Plurality of nucleic acid sequences of the Receptor of T lymphocytes or an amino acid sequence of the receptor specific T lymphocytes of yourMor of the Plurality of amino acid sequences of the Receptor of T lymphocytes in a selection Phase Sequence B.Classification of tumor specific T lymphocytes clones of: - providing a preparation of lymphocytes obtained from this Patient Isolating cells comprising such a Nucleic Acid SequenceReceptor tumor specific T lymphocytes selected or the amino acid sequence of the Receptor of tumor specific T lymphocytes selected this preparation of lymphocytes in aStage of isolation.Un método para proporcionar una preparación de linfocitos T específicos de tumor, que comprende las etapas de: a. seleccionar clones de linfocitos T específicos de tumor: - proporcionando una muestra tumoral obtenida de un paciente - aislando una preparación de ácido nucleico de dicha muestra tumoral en una etapa de aislamiento de ácido nucleico - obteniendo una pluralidad de secuencias de ácido nucleico del receptor de linfocitos T a partir de dicha preparación de ácido nucleico o una pluralidad de secuencias de aminoácidos del receptor de linfocitos T codificadas por dicha pluralidad de secuencias de ácido nucleico del receptor de linfocitos T - seleccionando una secuencia de ácido nucleico del receptor de lin
