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Use of the IdeS proteinase (from S, pyogenes) to treat autoimmune diseases and graft rejection
- 专利权人:
- HANSA MEDICAL AB
- 发明人:
- BJOERCK, LARS,HOLMDAHL, RIKARD,NANDAKUMAR, KUTTY SELVA
- 申请号：
- ES06754207
- 公开号：
- ES2380950T3
- 申请日:
- 2006.06.08
- 申请国别(地区):
- ES
- 年份:
- 2012
- 代理人:
- 摘要：
- An IdeS polypeptide or a polynucleotide encoding an IdeS polypeptide for use in a method of treatment or prevention of a disease or condition mediated by IgG antibodies, wherein the disease or condition is an autoimmune disease, transplant rejection, postoperative treatment or hemophilia acquired, and in the autoimmune disease is selected from Addison's disease, alopecia areata, ankylosing spondylitis, antiphospholipid syndrome, aplastic anemia, autoimmune gastritis, autoimmune hypoacusia, autoimmune hemolytic anemias, autoimmune hepatitis, autoimmune hypoparathyroidism, internal autoimmune hypophysitis, autoimmune ear disease autoimmune, autoimmune lymphoproliferative syndrome, autoimmune myocarditis, autoimmune oophoritis, autoimmune orchitis, autoimmune poliocrinoparia, Behcet's disease, bullous pemphigoid, cardiomyopathy, demyelinating polyneuropathy in chronic flamatoria, Churg-Strauss syndrome, celiac disease, Crohn's disease, CREST syndrome, Degos disease, acquired bullous epidemolysis, essential mixed cryoglobulinemia, giant cell arteritis, glomerulonephritis, Goodpasture's syndrome, Graves' disease, Gillan's syndrome -Barre, Hashimoto's thyroiditis, idiopathic thrombocytopenic purpura, inflammatory bowel disease, Kawasaki disease, Meniere's syndrome, mixed connective tissue disease, Mooren's ulcer, multiple sclerosis, myasthenia gravis, foliaceous pemphigus, vulgar pemphigus, pernicious anemia, polyarteritis noya polyglandular autoimmune syndrome type 1 (PAS-1), polyglandular autoimmune syndrome type 2 (PAS-2), polyglandular autoimmune syndrome type 3 (PAS-3), polymyositis / dermatomyositis, primary biliary cirrhosis, psoriasis, psoriatic arthritis, syndrome of Raynaud, Reiter's syndrome, rheumatoid arthritis, sarcoidosis, sclerod ermia, Sjörgren's syndrome, subacute thyroiditis, sympathetic ophthalmia, systemic lupus erythematosus, Takatasu arteritis, type 1 diabetes mellitus, vitiligo, Vogt-Koyanagi-Harda disease or Wegener granulomatosis.Un polipéptido I
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
