Prefilled syringe 1 is described. The prefilled syringe 1 comprises a tubular housing body 3 extending between a first opening 4 and a second opening 5 and comprising a first receiving chamber 8 and a second receiving chamber 8 which are airtightly separated from each other A cylindrical accommodating body 3 in which a containing chamber 9 is defined, a first solid substance or a liquid substance contained in the first accommodating chamber 8, and a second solid substance or a liquid substance accommodated in the cylindrical body 3 A first plug 6 and a second plug 7 which are arranged in the tubular body 3 so as to define the accommodating chamber 9 of the first plug 6 and the second plug 7 and are adapted to slide in the tubular body 3 , It is intended to reconstitute a second liquid substance contained in the second containing chamber 9 which is mixed with the first substance in the tubular body 3 and is injectable , And a second liquid substance. The syringe further comprises a dosing reservoir 20 having an inlet opening 21 and an outlet opening 22, the inlet opening 21 communicating with the first containing chamber 8 and the first containing chamber 8 is connected to the first plug 6 for administration And the inlet opening 21 of the reservoir 20. The dosing reservoir 20 is adapted to receive a portion of the injectable solution. The first plug 6 comprises a protrusion 16 adapted to pass through the inlet opening 21 of the administration reservoir 20 into the administration reservoir 20 and to release the above volume of solution from the administration reservoir 20.(FIG.事前充填注射器1が記載される。事前充填注射器1は、第1の開口4と第2の開口5との間に延在する筒状の収容本体3であって、互いに気密に分離された第1の収容チャンバー8及び第2の収容チャンバー9が内部に画定されている、筒状の収容本体3と、第1の収容チャンバー8に収容されている第1の固体物質又は液体物質と、筒状の本体3内で間に第2の収容チャンバー9を画定するように筒状の本体3内に配置されるとともに、筒状の本体3内を摺動するようになっている、第1のプラグ6及び第2のプラグ7と、第2の収容チャンバー9内に収容されている第2の液体物質であって、筒状の本体3内で第1の物質と混合され、注入可能な溶液を再構成することが意図される、第2の液体物質とを備える。注射器は、入口開口21及び出口開口22を有する投与用リザーバー20を更に備え、入口開口21は第1の収容チャンバー8と連通し、第1の収容チャンバー8が、
