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Method and system for reversal of interactions between hydrophobically modified biopolymers and vesicles or cell membranes
专利权人:
Matthew Dowling
发明人:
Matthew Dowling,Srinivasa R. Raghavan,Rakesh Kumar
申请号:
US13209399
公开号:
US08664199B2
申请日:
2011.08.13
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A method for reversing gelation of hydrophobically modified biopolymer attached to vesicle or cell membranes. The gelation of hydrophobically modified biopolymer attached to vesicles or cell membranes is reversed by application of a supramolecule, such as cyclodextrin, to the gelled composition. The supramolecule disrupts the interactions between the hydrophobically modified biopolymer and the vesicle or cell membrane, without affecting the structure of the membrane or the hydrophobically modified polymer to which the hydrophobic substituents are attached. A kit for treating wounds that includes a hydrophobically modified biopolymer and a supramolecule. The hydrophobically modified biopolymer is used to stop bleeding and the supramolecule is used to remove the hydrophobically modified biopolymer.
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