Paulraj Kirubakaran Lawrence,Russell F. Bey,Randy R. Simonson
申请号:
US15668946
公开号:
US20180015157A1
申请日:
2017.08.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides attenuated P. multocida strains that elicit an immune response in animal P. multocida, compositions comprising said strains, methods of vaccination against P. multocida, and kits for use with such methods and compositions. The invention further provides novel, genetically-engineered mutations in P. multocida hyaD and nanPU genes, which are useful in the production of novel attenuated P. multocida bacterial strains.