Marjan RAZANI,Adrian Linus Dinesh MARIAMPILLAI,Victor X. D. YANG,Michael KOLIOS
申请号:
US14141584
公开号:
US20140187904A1
申请日:
2013.12.27
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Provided herein are methods and systems to determine at least one mechanical property of a tissue sample and, based upon the determined at least one mechanical property, whether the tissue sample comprises atherosclerotic plaque. The method comprises generating a shear wave in an arterial tissue sample by applying an acoustic impulse thereto measuring propagation of the shear wave via an optical coherence elastography apparatus determining at least one mechanical property of the arterial tissue sample based on the propagation of the shear wave and comparing the at least one mechanical property of the arterial tissue sample to a reference data set to determine whether the arterial tissue sample comprises atherosclerotic plaque. A hybrid optical coherence tomography imaging/acoustic radiation force impulse system is disclosed.