Ethan W. Ojala;Jeffrey T.L. Smith;John A. Latham;Benjamin H. Dutzar;Leon F. Garcia-Martinez
发明人:
Leon F. Garcia-Martinez,Benjamin H. Dutzar,Ethan W. Ojala,Jeffrey T.L. Smith,John A. Latham
申请号:
US13834458
公开号:
US20130344068A1
申请日:
2013.03.15
申请国别(地区):
US
年份:
2013
代理人:
摘要:
This invention pertains to monovalent agents, including Fab fragments and monovalent monoclonal antibodies analogous to MetMab, having binding specificity to human Nerve Growth Factor (“NGF”), and methods of treating pain in an individual wherein there is no substantial increase in the inflammatory response of the individual following administration of the monovalent agents.