PYRIMIDINE-2-AMINE COMPOUNDS AND THEIR USE AS INHIBITORS OF JAK KINASES

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专利权人:

Ankush Argade;Somasekhar Bhamidipati;Ihab Darwish;Rajinder Singh;Jiaxin Yu;Hui Hong;Vadim Markovtosov;Sambaiah Thota;Jeffrey Clough;Pingyu Ding;Andy Atuegbu

发明人:

Somasekhar Bhamidipati,Jeffrey Clough,Ankush Argade,Rajinder Singh,Vadim Markovtosov,Pingyu Ding,Jiaxin Yu,Andy Atuegbu,Hui Hong,Ihab Darwish,Sambaiah Thota

申请号：

US13619843

公开号：

US20130018041A1

申请日:

2012.09.14

申请国别(地区):

US

年份:

2013

代理人:

摘要：

This invention is directed to compounds of formula (I):wheren, m, Y, R1, R2, R3, R4 and R5 are disclosed herein, as isolated stereoisomers or mixtures thereof, or pharmaceutically acceptable salts thereof； pharmaceutical compositions comprising the compounds of formula (I)； and methods of using the compounds and the pharmaceutical compositions in treating diseases or conditions associated with JAK2 activity.

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