FUENZALIDA;SEPULVEDA REYES, JUVENAL ANTONIO;FUENZALIDA DIAZ, MIGUEL ANGEL;BERRIOS CORNEJO, Miriam Rosa;GOLDEN OMEGA S.A.;SEPÚLVEDA REYES, Juvenal Antonio
发明人:
SEPULVEDA REYES, JUVENAL ANTONIO,BERRIOS CORNEJO, MIRIAM ROSA,FUENZALIDA DIAZ, MIGUEL ANGEL,MARKOVITS ROJAS, ALEJANDRO,HARTING GLADE, THOMAS FRANCIS
申请号：
CLCL2011/000082
公开号：
WO2012/088620A3
申请日:
2011.12.25
申请国别(地区):
CL
年份:
2012
代理人:
摘要：
A simple, efficient method for obtaining a concentrate that comprises around 80% by weight ω-3 fatty acid ethyl esters from a composition of material that contains ω-3 fatty acid esters or free ω-3 fatty acids, which comprises the following steps: a) placing the composition of material in contact with at least 96% by weight ethanol an alkali and metal hydroxide at a temperature between 60 and 200°C to form a liquid mixture that comprises fatty acid alkaline salts； b) cooling the liquid mixture to a temperature between 50 and -20°C to form a solid phase and a liquid phase, and separating the liquid phase from the solid phase； c) placing the liquid phase separated in step b) in contact with an acid to form an acidified mixture with a water content of less than 10%, in which the mixture consists of a solid phase that comprises the alkali metal salt of the acid and a liquid phase that comprises ω-3 fatty acids； d) heating the mixture from step c) to 50 to 150°C in the presence of an esterification catalyst to form a mixture that comprises ω-3 fatty acid ethyl esters； e) placing the mixture from step d) in contact with an alkali to form a neutralized mixture； f) distilling the neutralized mixture to obtain a distillate that comprises around 80% by weight ω-3 fatty acid ethyl esters.Un proceso eficiente y simple para obtener un concentrado que comprende sobre 80% en peso de etil ésteres de ácidos grasos ω-3 a partir de una composición de materia que contiene ésteres de ácidos grasos ω-3 o ácidos grasos ω-3 libres, que comprende las etapas de: a) contactar la composición de materia con etanol de al menos 96% en peso y un hidróxido de un metal alcalino a una temperatura entre 60 y 200 °C para formar una mezcla líquida que comprende sales alcalinas de ácidos grasos； b) enfriar la mezcla líquida hasta una temperatura entre 50 y -20 °C para formar una fase sólida y una fase líquida y separar la fase líquida de la fase sólida； c) contactar la fase líquida separada de la etapa b
