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N- (3-AMINO-QUINOXALIN-2-YL) -SULFONAMIDE DERIVATIVES AND THEIR USE AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS
专利权人:
Exelixis Inc
发明人:
Xu, Wei,Mac, Morrison B,Bajjelieh, William,Bannen, Lynne Canne,Brown, David S,Kearney, Patrick,Marlowe, Charles K,Nuss, John M,Tesfai, Zerom,Wang, Yong
申请号:
NO20082089
公开号:
NO341737B1
申请日:
2008.05.05
申请国别(地区):
NO
年份:
2018
代理人:
摘要:
The present invention comprises small molecule inhibitors of phosphatidylinositol 3-kinase (PI3K), which is associated with a number of malignancies such as ovarian cancer, cervical cancer, breast cancer, colon cancer, rectal cancer, and glioblastomas, among others. Accordingly, the compounds of the present invention are useful for treating, preventing, and/or inhibiting these diseases.Foreliggende oppfinnelse innbefatter småmolekyl inhibitorer av fosfatidylinositol 3-kinase (PI3K), som er assosiert med et antall malignanser slik som eggstokk kreft, cervical kreft, brystkreft, colon kreft, rektal kreft og glioblastomer, blant andre. Følgelig er forbindelsene i følge oppfinnelsen anvendelige for behandling, hindring og/eller inhibering av disse sykdommene.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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