COMPLEX OF ANGIOTENSIN RECEPTOR ANTAGONIST AND NEUTRAL ENDOPEPTIDASE INHIBITOR

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专利权人:

CHENGDU EASTON BIOPHARMACEUTICALS CO.; LTD.

发明人:

Ying WANG,Long HUANG,Yongzhe XIANG,Guodong CEN,Jianguo LI,Jianjing JIA,Qiangqiang LIU,Yang LIU,Haitao YANG,Qing DONG

申请号：

US15764244

公开号：

US20180318259A1

申请日:

2016.09.01

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Provided a complex of formula is [3-((1S, 3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl) propionate-(S)-3′-methyl-2′-(pentanoyl {2″-(tetrazol-5-ylate) biphenyl-4′-ylmethyl}amino) butyrate]6.XCa2+.YNa+.ZH2O, wherein X=1-3, Y=12-16, Z=9-18, and 2X+Y=18, and represented by formula (I). Also disclosed are the method of preparing the complex and the method of treating chronic heart disease using a medicament comprising the complex.

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