GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
GRANT, STEVEN,AKINSEYE, CHIKA,BHINDER, TEJINDER,HOOK, LAURA,LEWIS, ALAN PETER,ORECCHIA, MARTIN
申请号：
CA3064522
公开号：
CA3064522A1
申请日:
2018.05.24
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present disclosure relates to antigen binding compositions, includingantibodies, for treating interleukin 5 (IL-5)mediated diseases, and related methods. IL-5 is a secreted protein. IL- 5plays a role in a number of different diseases such as asthma,mild asthma, moderate asthma, severe asthma, mild eosinophilic asthma,moderate eosinophilic asthma, severe eosinophilic asthma,uncontrolled eosinophilic asthma, eosinophilic asthma, sub-eosinophilicasthma, chronic obstructive pulmonary disease, eosinophilicgranulomatosis with polyangiitis, hypereosinophilic syndrome, nasal polyposis,bullous pemphigoid, eosinophilic esophagitis, atopicdermatitis, moderate atopic dermatitis and severe atopic dermatitis. Thedisclosed compositions are suitable for treating these seriousIL-5 mediated diseases.
