A headphone device and a method for monitoring physiological condition are provided. The headphone device includes a headphone, a physiological sensor device and a physiological monitor device. The physiological sensor device is disposed on the headphone and senses a physiological data of a user, wherein the physiological data includes a pulse data and a body temperature data. The physiological monitor device is connected to the physiological sensor device and stores a normal physiological data range including a normal pulse range and a normal body temperature range. The physiological monitor device compares the physiological data with the normal physiological data range to output a physiological comparison signal, wherein the physiological monitor device compares the pulse data with the normal pulse range to output a pulse comparison signal, and the physiological monitor device compares the body temperature data with the normal body temperature range to output a temperature comparison signal.本發明提供一種生理狀況監控耳機裝置及方法。生理狀況監控耳機裝置包含耳機、生理感測裝置以及生理監控裝置。生理感測裝置設置在耳機上以感測使用者的生理數據,生理數據包含脈搏數據以及體溫數據。生理監控裝置連接生理感測裝置。生理監控裝置儲存正常生理數據範圍,正常生理數據範圍包含正常脈搏範圍以及正常體溫範圍。生理監控裝置比對生理數據與正常生理數據範圍,以輸出對應的生理比對訊號,其中生理監控裝置比對脈搏數據與正常脈搏範圍以輸出脈搏比對訊號,以及比對體溫數據與正常體溫範圍以輸出體溫比對訊號。