The present invention is a mass spectrometry (Mass spectrometer) pregnancy poisoning from biological samples ( plasma / serum ) using patient-specific diagnostic protein, Insulin like growth factor binding prtein, acid labile subunit (IGFBP, ALS), Alpha2-HS-glycoprotein (AHSG, Fetuin), Retinol binding protein 4 (RBP4), and alpha-1-microglobulin/bikunin precursor ( AMBP) and how to dig , etc. , related to the development of new diagnostic methods for labeling proteins with specific quantitative pregnancy poisoning them .본 발명은 질량분석기(Mass spectrometer)를 이용하여 생체시료(혈장/혈청)에서 임신중독환자 특이 진단단백질인 Insulin like growth factor binding prtein, acid labile subunit(IGFBP, ALS), Alpha2-HS-glycoprotein(AHSG, Fetuin), Retinol binding protein 4(RBP4), 및 alpha-1-microglobulin/bikunin precursor(AMBP) 등을 발굴하는 방법과, 이를 이용한 임신중독 특이표지단백질 정량을 위한 새로운 진단방법의 개발에 관한 것이다.
