This invention discloses a therapeutic post-injury pressure glove and a method to produce the same. The pressure glove is configured to apply pressure onto a plurality of pressure-receiving regions of an injured hand such that each pressure-receiving region receives a pressure within an upper bound and a lower bound determined therefor. In one embodiment, the pressure glove comprises a plurality of custom pressure-applying fabric portions each of which is configured to direct a pressure onto one of the pressure-receiving regions. A suitable fabric specific for each fabric portion is selected so that adequate pressure is provided on a wounded area while maintaining a low pressure on an intact part of the hand. The pressure glove is fabricated with a size less than the hands size by a reduction factor. The reduction factor and the set of selected fabrics are determined via obtaining a computed pressure distribution.