BUTTERICK, LISA A.,CUNNINGHAM, SCOTT D.,DICOSIMO, ROBERT,FOSSER, KARI A.,GRUBER, TANJA MARIA,HAYNIE, SHARON L.,PAYNE, MARK S.,ROUVIERE, PIERRE E.,WANG, HONG
申请号：
CA2822422
公开号：
CA2822422A1
申请日:
2011.12.19
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
Disclosed herein are compositions and methods to treat an oral cavity surface with a peracid-based benefit agent. The peracid benefit agent can be use for oral surface bleaching, whitening, disinfecting, destaining, deodorizing, decreasing or removing biofilm, and combinations thereof. The peracid is enzymatically generated from a carboxylic acid ester substrate using a CE-7 carbohydrate esterase having perhydrolytic activity (perhydrolase) in the presence of a source of peroxygen. A fusion protein comprising the perhydrolase coupled to a peptidic component having affinity for an oral cavity surface, either directly or through an optional linker, may be used to target the perhydrolytic activity to the oral cavity surface.
