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Procédé de production de liquide d'enrobage entérosoluble aqueux, préparation solide et son procédé de production
专利权人:
Shin-Etsu Chemical Co.; Ltd.
发明人:
申请号:
EP14169540.3
公开号:
EP2813218A1
申请日:
2014.05.22
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
An enteric preparation having a film-forming property and acid resistance is provided by using a simple and efficient method without using a special cooling apparatus. More specifically, provided is a method for producing an aqueous enteric coating liquid comprising the steps of: partially neutralizing an aqueous suspension comprising a cellulosic enteric material with an aqueous alkali solution, and mixing the partially-neutralized aqueous suspension with a plasticizer. Also provided is a solid preparation comprising a drug-comprising core and a coating portion obtained by coating the core with the produced aqueous enteric coating liquid. Further, provided is a method for producing a solid preparation, comprising respective steps in the method for producing an aqueous enteric coating liquid and a step of coating a drug-comprising core with the produced aqueous enteric coating liquid.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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