PROBLEM TO BE SOLVED: To obtain a liquid composition for the oral cavity exhibiting excellent usability (dischargeability and retention) and storage stability (appearance, pH and viscosity) and having high improving effect on the retention of a compounded medicinal component in the oral cavity.SOLUTION: The liquid composition for the oral cavity comprises (A) 0.5-2.0 mass% alginate having viscosity of 5-100 mPa s as 1.0 mass% aqueous solution at 20°C and a mass ratio of D-mannuronic acid [M] to L-guluronic acid [G] of 0.5-2.0, (B) 0.2-1.2 mass% carboxymethylcellulose sodium having an etherification degree of 0.8-1.6, (C) 0.05-0.5 mass% phosphate expressed by general formula (1): MnH3-nPO4 (M is Na or K and n is 1, 2 or 3) and (D) 45-90 mass% water wherein the mass ratio of (A)/(B) is 0.5-6.0 and the pH of the composition is 6.0-8.5.COPYRIGHT: (C)2008,JPO&INPIT【課題】優れた使用性(吐出性、保持性)、保存安定性(外観、pH、粘度)を有し、薬用成分を配合した場合に口腔内滞留性の向上効果が高い液状口腔用組成物の提供。【解決手段】(A)20℃における1.0質量%水溶液の粘度が5~100mPa・sで、D-マンヌロン酸〔M〕とL-グルロン酸〔G〕の含有比率が質量比で0.5~2.0であるアルギン酸塩を0.5~2.0質量%、(B)エーテル化度が0.8~1.6のカルボキシメチルセルロースナトリウムを0.2~1.2質量%、(C)式(1) MnH3-nPO4 (1)(MはNa又はK、nは1,2又は3。)で表されるリン酸塩を0.05~0.5質量%、(D)水分を45~90質量%含有し、(A)/(B)の質量比が0.5~6.0、pHが6.0~8.5である液状口腔用組成物。【選択図】なし
