The invention provides androgen receptor target agent (ARTA).This medicine defines a new subclass compound, and they are SARM (SARM).Found that several SARM compounds have the short male and anabolic activity of unexpected on-steroidal part to androgen receptor.Found that other SARM compound has the androgen antagonist activity of unexpected on-steroidal part to androgen receptor.The SARM compound is used for a) male contraception separately or as composition B) the multiple and hormone-related conditions of treatment, for example reduce (ADAM) relevant illness, as fatigue, depression, sexual desire reduction, sexual dysfunction, erective dysfunction, hypogonadism, osteoporosis, alopecia, anaemia, obesity, senile amyotrophy, osteopenia, osteoporosis, benign prostatic hyperplasia, mood and cognitive change and prostate cancer with old male sexs male sex hormone C) treatment reduces (ADIF) relevant illness with womens male sex hormone, as sexual dysfunction, sexual desire reduction, hypogonadism, senile amyotrophy, osteopenia, osteoporosis, mood and cognitive change, depression, anaemia, alopecia, obesity, endometriosis, mammary cancer, uterus carcinoma and ovarian cancer D) treat and/or prevent acute and/or chronic wasting disease E) prevent and/or treat xeropthalmus F) oral androgenic replacement therapy G) sickness rate of reduction prostate cancer stops prostate cancer or causes prostate cancer to disappear And/or h) apoptosis in the inducing cancer cell.
