John Stankus,Mikael Trollsas,Syed Hossainy,Zhang Liangxuan,Ed Berger,Stephen Pacetti,John L. Toner
申请号：
US14054797
公开号：
US20140046254A1
申请日:
2013.10.15
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A drug delivery balloon is provided comprising a balloon having a surface, and a coating disposed on at least a portion of the balloon surface, the coating including an cytostatic therapeutic agent, an excipient, and a plasticizer. In accordance with the present subject matter, at least 30% of the coating transfers from the balloon surface within two minutes after inflation of the balloon. Alternatively, at least 30% of the coating transfers from the balloon surface within one minute after inflation. The coating results in an effective pharmacokinetic profile of an cytostatic therapeutic agent in a vasculature or target tissue.
