The present invention is related to a composition for relieving joint inflammation. The present invention is also related to a method for treatment of joint inflammation, comprising a step of administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition. By means of inhibiting the COX-2 and NF-κB expression through the composition or the pharmaceutical composition with specific ratio, the joint inflammation and swelling could be reduced and the osteoclasts proliferation could be decreased to mitigate bone erosion, osteoporosis and degenerative arthritis.