The subject invention provides pharmaceutical compositions containing laquinimod or a pharmaceutically acceptable salt thereof, an isolated compound of N-ethyl-4-hydroxyl-1-methyl-5-(methyl(2,3,4,5,6-pentahydroxyhexyl)amino)-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide or a salt thereof, compositions containing N-ethyl-4-hydroxyl-1-methyl-5-(methyl(2,3,4,5,6-pentahydroxyhexyl)amino)-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide and methods of preparing the same.본 발명은 라퀴니모드 또는 이의 약제학적으로 허용가능한 염을 함유하는 약제학적 조성물, N-에틸-4-하이드록실-1-메틸-5-(메틸(2,3,4,5,6-펜타하이드록시헥실)아미노)-2-옥소-N-페닐-1,2-디하이드로퀴놀린-3-카복스아미드의 분리된 화합물 또는 이의 염, N-에틸-4-하이드록실-1-메틸-5-(메틸(2,3,4,5,6-펜타하이드록시헥실)아미노)-2-옥소-N-페닐-1,2-디하이드로퀴놀린-3-카복스아미드를 함유하는 조성물, 및 이들의 제조방법을 제공한다.
