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A NOVEL CREAM AND A PROCESS TO MAKE THE SAME
专利权人:
发明人:
MR SULUR SUBRAMANIAM VANANGAMUDI,MR SRINIVASAN MADHAVAN,MR CHULLIEL NEELAKANDAN NARAYANAN,MR KUPPUSAMY SENTHILKUMAR
申请号:
IN253/MUM/2010
公开号:
IN2010MU00253A
申请日:
2010.08.02
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
The present invention is directed to a medicinal composition for treating skin inflammations, fungalftacterial skin infections and related wounds, and also other skin wounds including those caused by burns. The cream also causes skin rejuvenation through an epithelisatiofl process. The cream comprises Chitosan. Clobetasol Propionate, Miconazole Nitrate and Fusidic acid. The invention also discloses a process to make the medicinal cream containing Fusidic Acid which is formed in situ from Sodium Fusidate as the starting raw material, wherein Sodium Fusidate is converted into Fusidic Acid under oxygen-free environment created using inert gas, preferably nitrogen, and Chitosan. The cream produced by the process of the present invention has greater shelf-life stability and the finer particle size of the API than the conventional creams containing Fusidic Acid. The cream produced by the process of the present invention contains Fusidic Acid as the API that has been formed in situ from Sodium Fusidate, Clobetasol Propionate and Miconazole Nitrate in a cream base comprising a preservative, an acid, a co-solvent, an emulsifier and a waxy material along with water, preferably purified water.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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