A system for planning, performing and/or evaluating the effectiveness of a therapeutic treatment of a target tissue includes at least one of a thermal conductivity probe including a microprobe sensor configured and adapted to measure a thermal conductivity in the target tissue in at least one direction or an electrical conductivity probe including a microprobe sensor configured and adapted to measure an electrical conductivity in the target tissue in at least one direction. The system further includes a multimeter operatively connected to at least one of the thermal conductivity probe or the electrical conductivity probe, the multimeter being configured and adapted to deliver energy to at least one of the thermal conductivity probe or the electrical conductivity probe, and a computer operatively connected to the multimeter.