Falko-Günter Falkner,Birgit Schafer,P. Noel Barrett,Thomas R. Kreil,Hartmut Ehrlich,Annett Hessel
申请号:
US13982524
公开号:
US20140050759A1
申请日:
2012.01.30
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to recombinant viral vectors and methods of using the recombinant viral vectors to induce an immune response to influenza A viruses. The invention provides recombinant viral vectors based, for example, on the non-replicating modified vaccinia virus Ankara. When administered according to methods of the invention, the recombinant viral vectors are designed to be cross-protective and induce heterosubtypic immunity to influenza A viruses.