Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides

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专利权人:

AMBRX; INC.

发明人:

MIAO, ZHENWEI,LIU, JUNJIE,NORMAN, THEA

申请号：

NZ59530306

公开号：

NZ595303A

申请日:

2006.12.13

申请国别(地区):

NZ

年份:

2013

代理人:

摘要：

Disclosed herein is a method of linking a polypeptide to a compound, said method comprising contacting a polypeptide comprising at least one non-natural amino acid with a compound comprising at least one aldehyde moiety to thereby form an amine linkage between the polypeptide and the compound, wherein the non-natural amino acid has a structure selected from the group as shown, wherein the substituents are as defined within the specification.

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