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SYSTEME D'ADMINISTRATION AGROCHIMIQUE BASE SUR DES HYBRIDES PEG-DENDRON AMPHIPHILES REAGISSANT AUX ENZYMES OU AU PH
专利权人:
RAMOT AT TEL-AVIV UNIVERSITY LTD.
发明人:
AMIR, ROEY JACOB,BUZHOR, MARINA,HARNOY, ASSAF JOSEF,ROSENBAUM, IDO,FRID, LIAT
申请号:
CA2960592
公开号:
CA2960592A1
申请日:
2015.02.25
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to an amphiphilic hybrid delivery system in micellar form for delivery of agrochemicals, based on a hydrophilic polyethylene glycol (PEG) polymer conjugated to a hydrophobic dendron, the dendron comprising at least one pH-dependent or enzymatically cleavable hydrophobic end group that is covalently attached to the dendron, wherein the micelle disassembles upon enzymatic or pH-dependent cleavage of the hydrophobic end group. The hydrophobic end group that is conjugated to the dendron may comprise an agrochemical, and/or the micelle may (non-covalently) encapsulate an agrochemical. The present invention further provides methods of use thereof and to a kit comprising same.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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