A power injector (200) is disclosed that includes a number of features to address leakage of contrast media from a syringe that may occur while operating the power injector (200), for instance when loading fluid into a syringe after being installed on a powerhead (210) of the injector (200) and/or when purging air from such a syringe. One or more drainage channels (240) may be incorporated on a faceplate mounting (234) which in turn receives a faceplate (310), which in turn receives a syringe. A cover assembly (260) may utilize a form-in-place gasket (274) between its top cover (262) and its bottom cover (290). A bezel (330) includes an overlay (334) that is disposed over a touch screen display (380) that is aligned with a display aperture (264) through the top cover (262), and the bezel (330) may include a gasket (350) to seal against the top cover (262).
