VON FIGURA, KURT,SCHMIDT, BERNHARD,DIERKS, THOMAS,HEARTLEIN, MICHAEL W,BALLABIO, ANDREA,COSMA, MARIA PIA
申请号:
NZ59642004
公开号:
NZ596420A
申请日:
2004.02.10
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Provided is a method of producing an activated sulfatase comprising cultivating an isolated sulfatase-producing cell, wherein the cell expresses: (i) a sulfatase and (ii) an over-expressed Formylglycine Generating Enzyme with a specified amino acid sequence wherein the ratio of active sulfatase to total sulfatase produced by the cell is increased by at least 5% over the ratio of active sulfatase to total sulfatase produced by the cell.