KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
发明人:
RHO, Mun Chual,LEE, Seung Woong,LEE, Soyoung,KIM, Sang-Hyun,PARK, Kwon Moo,LEE, Woo Song,JUNG, Kyungsook,PARK, Chan Sun
申请号:
WO2017KR11044
公开号:
WO2018066954(A1)
申请日:
2017.09.29
申请国别(地区):
世界知识产权组织国际局
年份:
2018
代理人:
摘要:
The present invention relates to a composition comprising oleanolic acid acetate as an active ingredient for preventing, alleviating, or treating renal toxicity induced by a medicine. Specifically, the present invention relates to a pharmaceutical composition for preventing or treating renal toxicity induced by a medicine, the composition comprising oleanolic acid acetate or a pharmaceutically acceptable salt thereof as an active ingredient, to a health functional food comprising the active ingredient for preventing or alleviating renal toxicity induced by a medicine, and to an anticancer supplement comprising the active ingredient. The oleanolic acid acetate of the present invention is derived from a natural material, and thus has no side effect and no toxicity and has excellent effects of preventing, alleviating, and treating renal toxicity induced by a medicine, especially, a platinum-based anticancer agent, and therefore, the oleanolic acid acetate of the present invention can be utilized as a pharmaceuti