PETERSSON, KARSTEN,ENGELL, KAREN MARGRETHE,JANSSON, JORGEN,NIELSEN, KIM TROENSEGAARD,ERIKSSON, ANDRE HUSS,MOORE, ANNE,VUCEN, SONJA,O'SULLIVAN, CAROLINE,CREAN, ABINA,OSULLIVAN, CAROLINE
申请号:
CA2979435
公开号:
CA2979435A1
申请日:
2016.03.16
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to a microneedle patch composition comprising one or more microneedles each comprising: (a) a tapered tip portion containing a therapeutically active ingredient dispersed in a matrix of a biodegradable polymer capable of providing sustained release of the therapeutically active ingredient over a period of at least two days after insertion of the microneedle or microneedles into the skin, and (b) a fast dissolving microneedle backing layer portion containing a water-soluble polymer overlayering the tip portion, said microneedle or microneedles being attached to and extending from an adhesive surface of a removable substrate.