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RECOMBINANT MEASURES VIRUS, PHARMACEUTICAL COMPOSITION, USE OF A PHARMACEUTICAL COMPOSITION, BACTERIAL CELL, METHOD TO PRODUCE A RECOMBINANT VIRUS AND USE
专利权人:
Centre National de La Recherche Scientifique;Institut Pasteur
发明人:
Chantal Combredet,Frédéric Tangy,Marie Pascale Frenkiel,Philippe Despres
申请号:
BRPI0407840
公开号:
BRPI0407840B1
申请日:
2004.02.26
申请国别(地区):
BR
年份:
2020
代理人:
摘要:
"purified polypeptide, purified polyclonal or monoclonal antibody, expression vector, purified polynucleotide sequence, use of a polynucleotide sequence, recombinant viral vector, recombinant measles virus, pharmaceutical composition, use of the same, host cell, method for producing a virus recombinant for the production of a recombinant virus, West Nile virus neutralization assay cell line, and method for treating and / or preventing an infection or disease associated with wnv or dengue virus in an animal ". the present invention relates to the development of viral vectors expressing different immunogens of the West Nile Encephalitis Virus (WNV, West Nile Encephalitis Virus) or the Dengue Virus which are capable of inducing protective cellular and humoral responses against infections with WNV virus or dengue fever. more specifically, the present invention relates to three (3) antigens from wnv (the secreted envelope glycoprotein (e), the heterodimer glycoproteins (pre-me) and the nsi protein) and the dengue virus (the glycoprotein ( e) from the secreted envelope, the heterodimer glycoproteins (pre-me) and the ns1 protein) and their use in vaccine, therapeutic and diagnostic applications."polipeptídeo purificado, anticorpo policlonal ou monoclonal purificado, vetor de expressão, seqüência de polinucleotídeo purificada, uso de uma seqüência de polinucleotídeo, vetor viral recombinante, vírus do sarampo recombinante, composição farmacêutica, uso da mesma, célula hospedeira, método para produzir um vírus recombinante para a produção de um vírus recombinante, linhagem de células ensaio de neutralização de vírus do nilo ocidental, e, método para tratar e/ou prevenir uma infecção ou doença associada com wnv ou vírus do dengue em um animal". a presente invenção refere-se ao desenvolvimento de vetores virais expressando diferentes imunógenos do virus da encefalite do nilo ocidental (wnv, west nile encephalitis virus) ou do vírus do dengue que são capazes de induzir resposta
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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