JOABSSON, FREDRIK,LINDEN, MARGARETA,THURESSON, KRISTER,TIBERG, FREDRIK
申请号：
PL09014796
公开号：
PL2206495T3
申请日:
2005.12.09
申请国别(地区):
PL
年份:
2013
代理人:
摘要：
The present invention relates to topical bioadhesive formulations comprising low viscosity, non-liquid crystalline, mixtures of: a) at least one neutral diacyl lipid and/or at least one tocopherol； b) at least one phospholipid； c) at least one biocompatible, oxygen containing, low viscosity organic solvent； wherein at least one bioactive agent is dissolved or dispersed in the low viscosity mixture and wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid for use in therapy. The invention additionally relates to the use of a preformulation of the invention in a method for the manufacture of a medicament.
