THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;CHILDREN'S HOSPITAL MEDICAL CENTER
发明人:
申请号：
EP05749675.4
公开号：
EP1750500B1
申请日:
2005.05.06
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
Use of neutrophil gelatinase-associated lipocalin (NGAL) as a therapeutic and in a method of treating, reducing, or ameliorating an injury selected from an ischemic injury, an ischemic-reperfusion injury, and a toxin-induced injury, to an organ in a patient. The invention includes administering to the patient NGAL in an amount effective to treat, reduce or ameliorate ischemic, ischemic-reperfusion, or toxin-induced injury to the organ, such as the kidney. A siderophore can be co-administered with the NGAL. The invention also relates to administering a sideophore to enhance a response to secretion of NGAL following an ischemic or toxin-induced injury to an organ in a patient.
