The invention relates to a transcatheter heart valve replacement (A62F2/2412), and in particular an orthogonally delivered transcatheter prosthetic valve frame having a tubular frame for mounting a flow control component wherein the valve frame is compressible to a compressed configuration for sideways or lateral introduction into the body using a delivery catheter for implanting at a desired location in the body, where the compressed configuration has a long-axis oriented roughly perpendicular to the central axis of the native annulus, wherein the long-axis of the compressed configuration of the valve is substantially parallel to a length-wise cylindrical axis of the delivery catheter, and wherein the valve has a height of about 5-60 mm and a diameter of about 25-80 mm.