Integrating optical systems and methods of use are described herein. In one embodiment, an integrating optical system comprises: a housing having a first and second portions and a chamber having a diffuse reflective material and a volume formed within the portions when coupled together. The portions are separable to allow insertion and removal of at least one light treatable object in and out of the chamber. At least one aperture is formed in the chamber to couple to a light source and to direct light from the light source to at least a first portion of the diffuse reflective material. At least one holding structure supports the object within the volume at a location, wherein the diffuse reflective material, the aperture and the location ensure that the light is diffusely reflected to integrate the light and impact the object with substantially uniform light without movement of the object.
