The present invention relates to a pesticide composition for preventing and treating fusarium head blight comprising, for each mu of a farmland, 1 to 150 parts by weight of validamycin and 1 to 20 parts by weight of metconazole. The pesticide composition of the present invention has a significant synergetic effect on preventing and treating fusarium head blight, can significantly improve the head blight preventing and treating effect and the head blight preventing and controlling capability of mankind； the pesticide composition significantly reduces the pollution level of DON toxin in wheat, reduces the dosage, the costs, environment pollution and pesticide residues, retards the drug resistance of wheat pathogenic fungus to metconazole to prevent and treat fusarium head blight； moreover, the pesticide composition prolongs the duration of action of validamycin, reduces the application frequency, and can also treat powdery mildew, rust disease, leaf blight, and sheath blight of Triticeae crops, thus the use costs of the pesticide are reduced； and due to a great reduction in the dosage of a chemical pesticide, the pesticide composition is environment-friendly .
