DERIVADOS DE 11-HIDROXILO SUBSTITUÍDOS EM 6 DE ÁCIDOS BILIARES E SEUS CONJUGADOS DE AMINOÁCIDO COMO MODULADORES DO RECETOR FARNESOIDE X

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专利权人:

INTERCEPT PHARMACEUTICALS; INC.

发明人:

ROBERTO PELLICCIARI

申请号：

PT14723820

公开号：

PT2997035T

申请日:

2014.05.14

申请国别(地区):

PT

年份:

2018

代理人:

摘要：

The present invention provides a compound of formula (I): or a pharmaceutically acceptable salt, solvate, or amino acid conjugate thereof, wherein R 1 is a hydroxy group and R 2 , R 3 , R 4 , R 5 , and R 6 are as described herein. The present invention relates generally to selective FXR agonists and to methods of making and using them.

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中国工程科技知识中心

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http://www.ckcest.cn/home/