Andreas Fischer,Dagmar Peters-Groth,Dagmar Lischke
申请号:
US14091399
公开号:
US08969368B2
申请日:
2013.11.27
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Crystalline, anhydrous hydrochloride salts of 4,5α-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one (oxymorphone) are disclosed and three polymorphic forms of these salts are reported. The invention further relates to a method for the production of such salts, a pharmaceutical composition comprising an effective amount of such a salt and such a salt as a medicament and for the treatment and/or prevention of pain.