GlaxoSmithKline Biologicals S.A.;ID Biomedical Corporation of Quebec
发明人:
BAUDOUX, Guy Jean Marie Fernand Pierre,BLAIS, Normand,CYR, Sonya L.,RHEAULT, Patrick,RUELLE, Jean Louis
申请号：
AU2014203636
公开号：
AU2014203636A1
申请日:
2014.07.03
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
#$%^&*AU2014203636A120140731.pdf#####Abstract The invention relates to a recombinant respiratory syncytial virus (RSV) antigen comprising an RSV F protein polypeptide whereby the F protein polypeptide (without a transmembrane domain) comprises an F2 domain and an F1 domain. The F protein polypeptide further comprises at least one modification that alters glycosylation comprising a substitution of one or more amino acids. The invention also provides for immunogenic compositions and methods of producing and using the antigens in the treatment of RSV infections and/or disease.
